蝮蛇抗栓酶是由蝮蛇蛇毒中提取的抗凝物质,具有溶解血栓的作用,临床上用于治疗各种血栓性疾病。但该药可增加出血倾向,临床上使用较大剂量时颇多顾虑。若从颈总动脉给药,便可提高脑内药物浓度而不增加剂量,对脑血栓形成的病人有利。我们用动物实验观察了这种给药方法的安全性问题 Agkistrodon antithrombotic enzyme is extracted from Agkistrodon acutus anticoagulant substances, with the role of thrombolytic, clinically used for the treatment of various thrombotic diseases. However, the drug can increase the bleeding tendency, a lot of clinical considerations when using larger doses. If administered from the common carotid artery, the concentration of the drug in the brain can be increased without increasing the dosage, which is beneficial for patients with cerebral thrombosis. We used animal experiments to observe the safety of this method of administration