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目的了解血尿酸合并代谢综合征对老年人冠状动脉病变程度的影响。方法回顾分析204例冠脉造影的老年患者血尿酸水平以及其他代谢异常对冠状动脉的影响,分析其意义。结果冠心病组患者与对照组患者比较血尿酸显著增高,但按冠脉病变的支数分组后,多支病变组血尿酸水平高于单支病变组,但未达到统计学意义。随着冠脉病变SYNTAX评分的增高血尿酸水平也增高,且高危病变组血尿酸显著高于低危病变组。结论高尿酸血症是冠心病的一个危险因素,与冠状动脉狭窄程度和病变支数相关,对冠状动脉严重程度的预测有一定的价值。
Objective To investigate the effect of serum uric acid and metabolic syndrome on the degree of coronary artery lesion in the elderly. Methods A retrospective analysis of 204 cases of coronary angiography in elderly patients with serum uric acid levels and other metabolic abnormalities on the coronary arteries, analysis of its significance. Results Serum uric acid was significantly increased in patients with coronary heart disease compared with patients in control group. However, the levels of serum uric acid in patients with multi-vessel disease were higher than those in patients with single coronary artery disease, but did not reach statistical significance. Serum uric acid levels also increased with the SYNTAX score of coronary lesions, and serum uric acid was significantly higher in the high-risk group than in the low-risk group. Conclusions Hyperuricemia is a risk factor of coronary heart disease, which is related to the degree of coronary artery stenosis and the number of lesions. It is of value to the prediction of the severity of coronary artery disease.