禽类成红细胞增多症病毒(AEV)是一种能诱发易感禽类患成红细胞增多症和纤维肉瘤的反转录病毒,也能转化组织培养的成纤维细胞和红细胞,转化作用需要AEV基因组的v-erb B基因,v-erb B编码一种糖蛋白,这种糖蛋白位于转化细胞的致密细胞内膜和细胞表面,目前还不能证实v-erd B蛋白具有何种酶活性,因而AEV的致癌机制仍是一个 Avian erythrocytosis virus (AEV) is a retrovirus that can induce susceptible avian polycythemia and fibrosarcoma, as well as tissue culture fibroblasts and erythrocytes, and transformation requires AEV genome v The -erb B gene, v-erb B, encodes a glycoprotein that is localized on the dense intracellular membranes and the cell surface of transformed cells and is not yet able to confirm which enzyme activity v-erd B has and thus causes carcinogenesis of AEV The mechanism is still one