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为研究交变磁场对大鼠坐骨神经横断损伤后再生修复的影响，切除２４只大鼠双侧坐骨神经股部的一部分，用硅管桥接神经两断端，其间距６ｍｍ，术后将大鼠随机分为实验组和对照组。实验组大鼠置于强度为０．５ｍＴ的交变磁场中饲养，分别于术后２、４、１６周观察神经再生状况。结果显示，术后２周可测出实验组再生神经冲动传导潜速率；用ＣＢ－ＨＲＰ逆行示踪在相应脊髓节段能标记出神经元胞体；术后４周和１６周，实验组大鼠坐骨神经传导潜速率明显快于对照组（Ｐ＜０．００１）。图像分析显示，实验组的再生神经轴突直径、髓鞘厚度和再生神经血管面积明显优于对照组；电镜下见实验组再生神经比对照组有较多的微丝、微管和线粒体。表明交变磁场可促进大鼠缺损的坐骨神经再生
In order to study the effect of alternating magnetic field on regenerative repair after sciatic nerve transection in rats, a part of bilateral sciatic nerve in 24 rats was excised. The two ends of the nerve were bridged with silicone tube. The distance between them was 6 mm. For the experimental group and control group. The experimental rats were housed in an alternating magnetic field of 0.5 mT and the nerve regeneration status was observed at 2, 4 and 16 weeks after operation. The results showed that the rate of regenerative nerve impulse conduction in the experimental group was measured 2 weeks after operation; neuronal soma was labeled in the corresponding spinal cord segments by retrograde tracing with CB-HRP; at 4 weeks and 16 weeks after operation, rats in experimental group Sciatic nerve conduction velocity was significantly faster than the control group (P <0.001). Image analysis showed that axonal diameter, thickness of myelin sheath and regenerative neurovascular area in the experimental group were significantly better than those in the control group. There were more microfilaments, microtubules and mitochondria in the regenerated nerve in the experimental group than those in the control group under the electron microscope. It shows that alternating magnetic field can promote the regeneration of sciatic nerve in rats