目的 :探讨介入化疗及栓塞治疗对大肠癌疗效的影响。方法 :选择术前经导管动脉内灌注化疗及明胶海绵栓塞治疗 ,2周后再手术切除的60例DukesC期大肠腺癌(以下简称介入手术组) ;与同期传统手术治疗的52例DukesC期大肠腺癌患者(以下称传统手术组) ,就术中出血、手术根治性切除率、肿瘤细胞有效坏死率 ,进行对照研究。结果 :手术根治性切除率 :介入手术组为83.3%(50/60) ,传统手术组为62 %(32/52)。术中出血 :介入手术组术中出血明显少于传统手术组(P<0.05)。介入手术组肿瘤细胞有效坏死率明显高于传统手术组(P<0.05)。结论 :介入化疗及栓塞治疗可阻塞肿瘤血供 ,促使肿瘤细胞的缺血坏死 ,减少手术中出血 ,提高手术切除率 Objective: To investigate the effect of interventional chemotherapy and embolization on the curative effect of colorectal cancer. Methods: Sixty DukesC stage colorectal adenocarcinomas resected two weeks after surgery were treated by intra-catheter infusion chemotherapy and gelatin sponge embolization (hereinafter referred to as interventional surgery group). 52 DukesC stage large intestine Adenocarcinoma patients (hereinafter referred to as the traditional surgery group), on intraoperative bleeding, surgical resection rate, the effective rate of tumor necrosis of the control study. Results: The radical resection rate was 83.3% (50/60) in the intervention group and 62% (32/52) in the conventional surgery group. Intraoperative bleeding: Interventional surgery group bleeding was significantly less than the traditional surgery group (P <0.05). The effective necrosis rate of tumor cells in the intervention group was significantly higher than that in the conventional surgery group (P <0.05). Conclusion: Interventional chemotherapy and embolization can block the blood supply of tumor, promote the necrosis of tumor cells, reduce the bleeding during operation and improve the rate of resection