目的 为探讨Isovist(伊索显)等渗造影剂对脊髓造影诊断的价值,进行临床观察。方法 患者侧卧于X线机诊视床上,选择椎隙穿刺蛛网膜下腔,2min内均匀注入Isovist 10ml,俯卧及观察拍片。结果 47例行手术治疗,与造影诊断完全符合者45例,占95.7％。脊髓造影不良反应率为20.3％,一般3天内症状消失。结论Isovist脊髓造影具有不良反应轻、发生率低、诊断符合率高等特点,是一种安全可行的椎管内疾病诊断方法。 Objective To investigate the value of Isovist isotonic contrast agent in the diagnosis of myelography. Methods The patient was lying on the bed of the X-ray machine and selecting the puncture of the subarachnoid space. In 2 minutes, the patient was injected with 10 ml of Isovist and the patient was prone and observed. Results 47 cases underwent surgical treatment, which was completely consistent with the diagnosis of angiography in 45 cases (95.7%). Myelography adverse reaction rate was 20.3%, the general symptoms disappear within 3 days. Conclusion Isovist myelography has the characteristics of mild adverse reactions, low incidence and high diagnostic accuracy. It is a safe and feasible method for the diagnosis of spinal canal diseases.