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目的:探讨分析阿奇霉素序贯疗法治疗矽肺并发衣原体肺炎的临床疗效。方法:选取我院于2011-2014年收治的74例矽肺并发衣原体肺炎的患者,随机分为对照组和观察组,对照组在常规治疗的基础上给予红霉素静点,观察组在常规治疗的基础上给予阿奇霉素序贯疗法,对两组患者的临床疗效,总疗程及不良反应进行比较。结果:观察组总有效率94.7%,高于对照组81.5%(P<0.05),观察组咳退热时间、咳嗽消失、肺部罗音消失时间及总疗程均低于对照组(P<0.05),观察组患者治疗期间胃肠道反应、皮疹、局部疼痛发生率低于对照组(P<0.05)。结论:阿奇霉素序贯疗法治疗矽肺并发衣原体肺炎效果好,见效快,副作用少等优点,是一种很好的治疗方案。
Objective: To investigate the clinical efficacy of sequential therapy of azithromycin in the treatment of silicosis complicated with chlamydial pneumonia. Methods: Seventy-four patients with silicosis complicated with Chlamydia pneumonia admitted in our hospital from 2011 to 2014 were randomly divided into control group and observation group. The control group was given erythromycin intravenous injection on the basis of conventional treatment. The observation group received routine treatment On the basis of sequential therapy given azithromycin, the two groups of patients with clinical efficacy, the total duration of treatment and adverse reactions were compared. Results: The total effective rate in the observation group was 94.7%, higher than that in the control group (81.5%, P <0.05). In the observation group, the cough, the disappearance of cough, the disappearance of pulmonary rales and the total course of treatment were lower than those in the control group ). The incidence of gastrointestinal reactions, skin rashes and local pain during the treatment group in the observation group was lower than that in the control group (P <0.05). Conclusion: Sequential azithromycin treatment of silicosis complicated with Chlamydia pneumonia is effective, quick, less side effects, is a good treatment.