卵巢癌是女性最常见的恶性肿瘤之一,手术和化学治疗是主要的治疗方法。目前用于卵巢癌化疗的药物有20余种,有60%~70%的病人对首次传统经验化疗方案有良好反应〔1〕。然而卵巢癌(尤其是晚期卵巢癌)的预后仍然很差。多数病人在治疗过程中出现耐药。人们期待能够通过体外药物敏感 Ovarian cancer is one of the most common malignant tumors in women. Surgery and chemotherapy are the main treatments. Currently used for ovarian cancer chemotherapy drugs have more than 20 kinds, 60% to 70% of patients on the first traditional empirical chemotherapy regimens have a good response 〔1〕. However, the prognosis of ovarian cancer (especially advanced ovarian cancer) remains poor. Most patients show resistance during the course of treatment. People expect to be drug-sensitive through in vitro drugs