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5. Small RNAs： Emerging key players in DNA double-strand break repair

Small RNAs： Emerging key players in DNA double-strand break repair

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：nilaopopodi

【摘 要】

：

DNA double-strand break(DSB)is the most deleterious form of DNA damage and poses great threat to genome stability.Eukaryotes have evolved complex mechanisms to

【作 者】

：

BA ZhaoQing QI YiJun 

【机 构】

：

Tsinghua-PekingCenterforLifeSciences

【出 处】

：

中国科学：生命科学英文版

【发表日期】

：

2013年10期

【关键词】

：

DNA双链断裂 小分子RNA DNA损伤 断裂修复 细胞周期检查点 人物 DSB 生物进化 DNA damage  small RNAs  diRNA  Dic 

【基金项目】

：

supported in part by China National Funds for Distinguished Young Scientists(31225015),National Key Scientific Research Program of China(2012CB910900)to Qi YiJun

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DNA double-strand break(DSB)is the most deleterious form of DNA damage and poses great threat to genome stability.Eukaryotes have evolved complex mechanisms to repair DSBs through coordinated actions of protein sensors,transducers,and effectors.DSB-induce

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