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[目的]观察评价达立通颗粒治疗残胃炎及吻合口炎的疗效和安全性。[方法]本研究共纳入有明确的胃肠病史,经胃镜确诊的残胃炎及残胃吻合口炎82例,随机分为达立通颗粒组(治疗组)42例和多潘立酮组(对照组)40例,分别予以达立通颗粒及多潘立酮片(吗丁林)治疗4周。治疗前后行胃镜及或组织病理病理检查,并对上腹疼痛;上腹烧灼感;腹胀;恶心呕吐;食欲不振;排便困难,六方面的症状予以评分。不良反应在治疗过程中及治疗后咨询记录。[结果]治疗后2组患者症状均有改善,治疗组总有效率:85.71%;对照组总有效率:60.00%;2组从临床症状及胃镜组织形态改善方面比较差异均有统计学意义(P<0.05)。[结论]达立通颗粒治疗残胃及吻合口炎优于多潘立酮。
[Objective] To observe and evaluate the efficacy and safety of Dalitong granules in the treatment of residual gastritis and anastomotic stomatitis. [Methods] A total of 82 gastric residual gastritis and stomachache with stomachache confirmed by gastroscope were enrolled in this study. They were randomly divided into two groups: the control group (42 cases) and the control group (42 cases) Forty patients were treated with Dalitong granules and domperidone tablets for 4 weeks respectively. Gastroscopy before and after treatment or histopathological examination and abdominal pain; upper abdominal burning sensation; abdominal distension; nausea and vomiting; loss of appetite; defecation difficulties, the symptoms of six to be scored. Adverse reactions in the course of treatment and after treatment consulting records. [Results] The symptoms of both groups improved after treatment. The total effective rate was 85.71% in the treatment group and 60.00% in the control group. There were significant differences in clinical symptoms and gastroscopic morphology between the two groups P <0.05). [Conclusion] Dalitong granule is superior to domperidone in the treatment of residual stomach and anastomotic stoma.