对小鼠、新西兰兔多点皮内注射及肌肉注射 ,然后测定其抗体效价 ,以研究重组戊型肝炎疫苗的性能。结果显示 ,小鼠在免疫 7d后开始产生抗体 ,2周抗体阳性率为 80 % ,4周抗体阳性率达 10 0 % ,新西兰兔从第二周后开始产生抗体 ,第三周达到高峰 ,抗血清在 1:6 4 0 0稀释度的阳性率 Mice, New Zealand rabbits were injected intradermally and intramuscularly, and their antibody titers were measured to study the performance of the recombinant hepatitis E vaccine. The results showed that the mice started to produce antibodies after 7 days of immunization. The antibody positive rate was 80% at 2 weeks and 10% at 4 weeks. New Zealand rabbits began to produce antibodies after the second week, reached the peak at the third week, Serum at a 1: 640 dilution rate of the positive rate