目的研究脑梗死患者颈动脉粥样硬化斑块与血脂及纤维蛋白原(Fib)水平的关系。方法对39例脑梗死患者和36例健康体检者行彩色多普勒超声检查,同时检测两组患者的血脂和Fib水平。结果脑梗死组的TC、LDL、Fib水平明显高于正常对照组(P均<0.01)。结论颈动脉粥样硬化斑块与脑梗死发生有密切关系;TC、LDL与动脉粥样硬化斑块的发生密切相关;血浆Fib水平增高可促使脑梗死发生。 Objective To investigate the relationship between carotid atherosclerosis plaque and serum lipids and fibrinogen (Fib) levels in patients with cerebral infarction. Methods Thirty-nine patients with cerebral infarction and 36 healthy subjects underwent color Doppler ultrasonography. The levels of serum lipids and Fib were also measured. Results The levels of TC, LDL and Fib in cerebral infarction group were significantly higher than those in normal control group (all P <0.01). Conclusions Carotid atherosclerosis plaque is closely related to cerebral infarction. TC and LDL are closely related to the development of atherosclerotic plaque. Increased plasma Fib levels may induce cerebral infarction.