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微囊胰岛的研究已获成功,但尚未见微囊垂体的研究报道。我们采用海藻酸钠和多聚赖氨酸等,用自制的微囊化器具,成功地制成微囊垂体,这种微囊直径约1.5mm,微囊膜对免疫球蛋白不通透(分子量>15万),但对垂体激素(分子量2万左右)能透过。囊外TSH、PRL、GH在3h内有70％透入囊内,6h后囊内外浓度达到平衡。人血清白蛋白(分子量7万左右)3h透入50％,
The study of microencapsulated islets has been successful, but no study has been reported on the microcapsule pituitary. We used sodium alginate and polylysine, etc., and made microcapsule pituitary successfully with a homemade microencapsulated device. The diameter of this microcapsule is about 1.5mm, and the microcapsule membrane is not transparent to immunoglobulins (molecular weight). >150,000), but it can penetrate pituitary hormones (molecular weight about 20,000). Extra-capsular TSH, PRL, and GH had 70% penetration into the capsule within 3 hours, and after 6 hours, the concentration inside and outside the capsule reached equilibrium. Human serum albumin (molecular weight about 70,000) penetrates 50% for 3 hours,