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目的:探讨卵巢囊肿囊液中的肿瘤标记物的分布与临床意义。方法:在超声介入治疗过程中认真分析卵巢囊肿囊内容物,包括常规生化和细胞学检查,尤其注重分析癌胚抗元(CEA)的含量与分布,以及与血清中和硬化治疗后的囊液中的含量做比较。个别高度怀疑恶性病变的患者施行了手术。结果:6例为功能性囊肿无明确的病理学发现。24例浆液性囊腺瘤中2例CEA水平超过正常标准。粘液性囊腺瘤,囊性畸胎瘤和巧克力囊肿均表现为CEA水平增高。炎性积液中1例CEA水平增高。明显增高的病例中囊液的CEA水平均高于血清水平。治疗后的囊液中CEA明显低于治疗前,并低于正常值。结论:卵巢囊肿囊液的CEA具有较高的敏感性,对介入性诊断和治疗的观察有比较明确的临床意义。
Objective: To investigate the distribution and clinical significance of tumor markers in ovarian cyst fluid. Methods: The contents of ovarian cysts, including routine biochemical and cytological examinations, were carefully analyzed during the ultrasound interventional treatment. The CEA content and distribution were analyzed in detail. The cyst fluid In the content comparison. Some highly suspected malignant lesions of patients underwent surgery. Results: There were no definite pathological findings in 6 cases of functional cysts. Two of the 24 serous cystadenomas had CEA levels above the normal level. Mucinous cystadenoma, cystic teratoma and chocolate cysts showed CEA levels increased. 1 case of inflammatory effusion CEA levels increased. Significantly higher cases of CEA levels of cystic fluid were higher than serum levels. CEA in cystic fluid after treatment was significantly lower than before treatment and lower than normal. Conclusion: The CEA of ovarian cyst fluid is highly sensitive and has definite clinical significance for the interventional diagnosis and treatment.