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目的了解鲍曼不动杆菌临床分布及耐药情况,为临床合理用药、控制感染提供依据。方法对2013~2015年该院住院患者送检标本中分离的鲍曼不动杆菌采用K-B法检测分离标本中鲍曼不动杆菌耐药率并进行数据统计。结果 2013~2015年共分离鲍曼不动杆菌3 562株,主要来源于痰液,占73.50%(2 618/3 562),且主要分布于重症医学科、胸外科和神经内科。对各种抗菌药物耐药率呈逐年上升趋势,仅对左氧氟沙星较为敏感。结论鲍曼不动杆菌耐药日益严重,加强对重点科室合理用药的监管、观测鲍曼不动杆菌的耐药迁徙对临床正确使用抗菌药物、控制感染及延缓耐药具有重要意义。
Objective To understand the clinical distribution and drug resistance of Acinetobacter baumannii and to provide a basis for rational clinical use and infection control. Methods The Acinetobacter baumannii isolated from the inpatients in 2013 ~ 2015 in our hospital were tested for K-B resistance and the data were collected. Results A total of 3 562 Acinetobacter baumannii strains were isolated from 2013 to 2015, mainly from sputum, accounting for 73.50% (2 618/3 562). They were mainly distributed in the departments of critical care, thoracic surgery and neurology. The rate of resistance to various antimicrobial drugs showed an upward trend year by year, levofloxacin only more sensitive. Conclusion Acinetobacter baumannii is becoming more and more drug-resistant. It is important to strengthen the supervision of rational drug use in key departments and to observe the drug-resistant migration of Acinetobacter baumannii. It is of great significance to correctly use antimicrobial drugs, control infection and delay drug resistance in clinic.