急性髓系白血病(AML)是一类异质性疾病,是在多种致病因素打击下的造血干祖细胞遗传学变异累积的结果。细胞和分子遗传学异常是其致病基础,同时也是影响其预后的重要因素。细胞遗传学染色体核型分析是评估预后并指导治疗方案选择制定的重要依据,然而近年来发现,通过染色体核型评估预后仍欠精确,因为即使在同一预后分层,预后也可能有很大差别,在核型正常的中等预 Acute myeloid leukemia (AML) is a heterogeneous disease that results from the accumulation of genetic variations in hematopoietic stem and progenitor cells under various pathogenic factors. Cell and molecular genetic abnormalities are the basis of its pathogenesis, but also affect the prognosis of an important factor. Cytogenetics Karyotype analysis is an important basis for assessing the prognosis and guiding the development of treatment options. However, it has been found in recent years that prognosis based on karyotype assessment remains poorly defined because the prognosis may be quite different even in the same prognosis stratification , Medium normal in karyotype