传染性肝炎的病原,早在40年前即知其为病毒,然迄今尚未分离成功。自从1963年发现 H.A.A 并确定其为乙型肝炎病毒的标记以来,对本病有较大的突破。为诊断、治疗乃至控制消灭本病方面提供了重要资料,今简要综述于后。一、乙型肝炎抗原的历史与命名1963年,布伦氏(Blumberg)等在一名澳大利亚人血中发现一新抗原,与一例经多次输血产生低密度β-脂蛋白沉淀素的血友病者的血清可发生淀集;其它人中则无反 The pathogen of infectious hepatitis, known as a virus as early as 40 years ago, has so far not been isolated successfully. Since the discovery of H.A.A in 1963 and its identification as a hepatitis B virus, there has been a major breakthrough in this disease. For the diagnosis, treatment and even the control of the disease to provide an important piece of information, this brief review later. I. History and Nomenclature of Hepatitis B Antigen Blumberg et al. Found a new antigen in an Australian blood in 1963, in contrast to an example of a hemophilia that had been transfused to produce low-density β-lipoprotein precipitin Serum of the patient can occur in the collection; other people have no reaction