青光眼的治疗,从匹罗卡品和毒扁豆碱用于临床到20世纪70年代的一百多年来,几乎无甚进展。1976年,Phillips等发现用心得安静脉注射和口服给药能降低眼压,遂用其治疗青光眼。此后,有关β-肾上腺素能受体阻滞剂治疗青光眼的报告日趋增加,至今该类制剂已逐渐发展成为新型的降眼压药物。噻吗心安(Timolol)就是这类药物中的一种。由于它与其它同类药物如心得安(Properanol)、氨酰心安 Treatment of glaucoma, with almost no progress from more than 100 years of clinical use of pilocarpine and physostigmine in the 1970s, In 1976, Phillips and others found that intravenous injection and oral administration can reduce intraocular pressure, then use it to treat glaucoma. Since then, the report of β-adrenergic receptor blocker treatment of glaucoma has been increasing, so far such preparations have gradually developed into a new type of antihypertensive drugs. Timolol is one of these drugs. Because it and other similar drugs such as Proontide (Properanol), Atenolol