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注射剂在生产配制过程中,常由于药物的称量或溶媒的量取有误差,使其半成品的含量偏高或偏低,这时就需要补加溶媒或补加药物,进行含量的调整。在调整过程中,往往通过简单计算收不到满意效果。笔者根据溶液稀释的有关理论,推导出含量调整计算公式,井阐明公式的应用方法,现介绍如下。1 设计:C_0——为标示含量(g/ml)。即制剂中某药物的标示含量。C~9—为实际测得药物的含量(g/
Injection preparation in the production process, often due to the amount of drug or solvent measurement error, so that the content of semi-finished products is high or low, then you need additional solvent or additional drugs, the content adjustment. In the adjustment process, often through a simple calculation can not receive satisfactory results. According to the theory of solution dilution, the author deduced the formula for calculating the content, and clarify the application of the formula, are presented below. 1 Design: C_0-- marked content (g / ml). That is, the labeled content of a drug in the preparation. C ~ 9 - for the actual measured drug content (g /