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目的:研究不同年龄及病理类型对双侧卵巢囊肿患者术前及术后短时间内血清AMH水平的影响。方法:2010年8月~2011年10月因双侧卵巢囊肿行腹腔镜手术患者共30例,比较不同年龄、病理类型及时间点血清AMH水平的差异。结果:术前AMH水平与年龄呈负相关(R=-0.589,P<0.001),20~25岁的女性患者AMH水平最高(2.64±0.48)ng/ml,36~40岁的女性患者AMH降至(1.44±0.73)ng/ml;术前AMH水平与病理类型有关,非内异症组和内异症组术前AMH水平分别为(2.61±0.54)ng/ml和(1.79±0.68)ng/ml,差别有统计学意义(P<0.05);术后3天AMH仅为术前的23.62%,而术后1月可恢复到34.67%。结论:AMH可作为判断卵巢功能变化的指标,临床应用需结合年龄综合考虑;腹腔镜卵巢囊肿剥除术短时间内对卵巢功能有影响,但术后仍可逐渐恢复。
Objective: To study the effect of different age and pathological types on serum AMH levels in patients with bilateral ovarian cysts before and after operation for a short period of time. Methods: From August 2010 to October 2011, 30 patients underwent laparoscopic surgery for bilateral ovarian cysts. The differences of serum AMH levels at different ages, pathological types and time points were compared. Results: The preoperative AMH level was negatively correlated with age (R = -0.589, P <0.001). The AMH level was the highest in women aged 20-25 years (2.64 ± 0.48) ng / ml, and the AMH in women aged 36-40 years (1.44 ± 0.73) ng / ml. The preoperative levels of AMH were correlated with pathological types. The preoperative levels of AMH in non-endometriosis group and endometriosis group were (2.61 ± 0.54) ng / ml and (1.79 ± 0.68) ng / ml, the difference was statistically significant (P <0.05); AMH 3 days after surgery was only 23.62% before surgery, but after January 1, the recovery was 34.67%. Conclusion: AMH can be used as an index to judge the ovarian function. Clinical application should be considered in combination with age. Laparoscopic ovarian cyst excision can affect ovarian function in a short time, but can recover gradually after operation.