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Myopia is the most common refractive disorder.High myopia affects 27%-33% of all myopic eyes in Asia.1,2 The pathologic myopia (PM) is the most severe vision-threatening phenotype of high myopia.3 It is also the second most common cause of choroidal neovascularization (CNV) in Asia.Unlike age-related macular degeneration (AMD) which mostly effecting elders,PM causes severe vision loss in young adults,resulting in a significant impairment of their working ability.4 PM has become the second leading cause of low vision and blindness particularly among those aged at 40-49 years in some Asia countries.