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目的比较９９ｍＴｃ－甲氧基异丁基异腈（ＭＩＢＩ）心肌ＳＰＥＣＴ显像与电子束ＣＴ（ＥＢＣＴ）冠状动脉钙化（ＣＡＣ）定量积分对冠心病诊断的价值。方法２１例经冠状动脉造影确诊的病人同时进行９９ｍＴｃ－ＭＩＢＩ心肌ＳＰＥＣＴ显像（潘生丁介入试验）及ＥＢＣＴ检查，以冠状动脉造影为金标准，以决策矩阵法评价心肌ＳＰＥＣＴ及ＥＢＣＴ的临床应用价值。结果心肌ＳＰＥＣＴ显像灵敏度为９１％，特异性为８０％，准确性为８６％；ＥＢＣＴ以钙化积分≥１００为阳性标准，则其灵敏度、特异性和准确性分别为５５％、１００％及７６％。结论心肌ＳＰＥＣＴ显像和ＥＢＣＴ冠状动脉ＣＡＣ定量积分法均为非创伤性检查法，对冠心病的诊断各具优势及局限性，有互补作用。
Objective To compare the diagnostic value of 99mTc-methoxyisobutylisonitrile (MIBI) myocardial SPECT imaging and electron beam computed tomography (EBCT) coronary artery calcification (CAC) in the diagnosis of coronary heart disease. Methods Twenty-one patients diagnosed by coronary angiography underwent 99mTc-MIBI myocardial SPECT imaging (SPECT) and EBCT. Coronary angiography was used as the gold standard to evaluate the clinical value of myocardial SPECT and EBCT. Results The sensitivity, specificity and accuracy of myocardial SPECT imaging were 91%, 80% and 86%, respectively. The sensitivity, specificity and accuracy of EBCT were 55%, 100% and 76% respectively %. Conclusions Myocardial SPECT imaging and CBC quantitative coronary angiography are both noninvasive methods. The diagnosis of coronary heart disease has its own advantages and limitations with complementary effects.