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胰解痉多肽(Pancreatic SpasmolyticPolypeptide PSP)是不久前从猪胰脏中分离到的一种新的活性蛋白质,目前国外正研究其供医疗药用,该项工作已引起我国药学工作者的注意。化学:胰解痉多肽由106个氨基酸残基组成,有14个半胱氨酸,但无游离巯基。氨基酸顺序与已知的其他胰脏活性蛋白质或多肽比较,未见有相同之处。分布:用放射免疫法测定猪各个器官、血浆和胰液中的胰解痉多肽的含量,发现胰脏是唯一富含胰解痉多肽的器官。胰脏中胰解痉多肽的浓度约为0.1mg/g湿
Pancreatic SpasmolyticPolypeptide PSP is a new active protein isolated from porcine pancreas not long ago. At present, it is being studied for medicinal purposes in foreign countries. This work has drawn the attention of Chinese pharmacologists. Chemistry: Pancreatic spasm polypeptide consists of 106 amino acid residues, 14 cysteines, but no free thiol. Amino acid sequence compared with other known pancreatic active protein or polypeptide, no similarities were found. Distribution: Determination of pancreatic spasmolytic peptide content in various organs, plasma and pancreatic juice by radioimmunoassay and found that the pancreas is the only organ rich in pancreatic antispasmodic peptides. Pancreatic antispasmodic peptide concentration of about 0.1mg / g wet