本文设计制作了一种对烯丙基杯 [4 ]芳烃涂层毛细管。用于毛细管电泳分离的结果表明 ,此管能分离 5 羟色胺 ( 5 HT)、多巴胺 (DA)、去甲肾上腺素 (NE)、肾上腺素 (E)等结构相近的单胺类神经递质 ,而无涂层管则不能。本涂层管在pH4～ 9范围内的电渗较无涂层管下降约 75% ,且当pH <8时 ,电渗随pH的变化接近于线性关系 ,有利于高重现分离。杯芳烃涂层毛细管不降低紫外检测灵敏度。其主要问题是酚羟基对胺类仍有吸附 (或静电 )作用 This paper has designed a capillaries coated with allyl-calix [4] arene. The results of capillary electrophoresis separation showed that this tube could separate monoamine neurotransmitters with similar structures such as 5 HT, DA, NE and epinephrine No coating tube can not. The electroosmosis of the coated tube in the range of pH4 ~ 9 is about 75% lower than that of the uncoated tube. When the pH is less than 8, the electroosmosis changes with the pH close to a linear relationship, which is conducive to high reproducibility. Calixarene coated capillaries do not reduce UV detection sensitivity. The main problem is the phenolic hydroxyl on the amine is still adsorption (or electrostatic) role