新近研究发现,心血管疾病患者血中内皮素—1(ET—1)水平明显增高,ET—1收缩冠状动脉及周围血管使心肌缺血及血压增高,但受多种因素影响,并非所有心血管疾病患者血中ET—1水平均增高,本文通过监测心血管疾病ET—1水平并进行分析。 1 对象与方法 1.1 研究对象:心血管疾病组39例,男25例,女14例,年龄39～80(平均60.56)岁,其中高血压病14例,冠心病25例。对照组25例,男12例,女13例,年龄16～79(平均50.00)岁,其中肺炎7例,慢性支气管炎7例,慢性胃炎11例。 Recent studies have found that in patients with cardiovascular disease, the level of endothelin-1 (ET-1) is significantly increased, and the coronary arteries and peripheral blood vessels of ET-1 shrink myocardial ischemia and blood pressure, but not all heart Blood levels of ET-1 are elevated in patients with vascular disease. In this paper, ET-1 levels in cardiovascular disease were monitored and analyzed. 1 Subjects and Methods 1.1 Subjects: Cardiovascular disease group 39 cases, 25 males and 14 females, aged 39 to 80 (average 60.56) years, of which 14 cases of hypertension, 25 cases of coronary heart disease. Control group of 25 patients, 12 males and 13 females, aged 16 to 79 (average 50.00) years, of which 7 cases of pneumonia, chronic bronchitis in 7 cases, 11 cases of chronic gastritis.