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目的通过观察2型糖尿病患者尿微量白蛋白与血脂的相关性,探讨血脂异常与糖尿病肾病的关系。方法选取48例2型糖尿病患者,根据尿mAlb/Cr结果分为无微量白蛋白尿组(DM组)及伴有微量白蛋白尿组(DN组)。检测甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)等,观察各项指标与尿mAlb/Cr的关系。对照组20例。结果对照组TG、TC、LDL与DN组比较,均明显降低(P<0.05),DM组TG、TC、LDL明显低于DN组(P<0.05)。结论 2型糖尿病患者血脂异常是糖尿病肾病的重要危险因素之一。
Objective To observe the relationship between urinary albumin and blood lipids in type 2 diabetic patients and explore the relationship between dyslipidemia and diabetic nephropathy. Methods Forty-eight patients with type 2 diabetes mellitus (DM) were divided into two groups according to the results of urine mAlb / Cr: microalbuminuria group (DM group) and microalbuminuria group (DN group). The triglyceride (TG), total cholesterol (TC), high density lipoprotein (HDL) and low density lipoprotein (LDL) were measured to observe the relationship between each index and urine mAlb / Cr. Control group of 20 cases. Results TG, TC, LDL in DN group were significantly lower than those in DN group (P <0.05). TG, TC and LDL in DM group were significantly lower than those in DN group (P <0.05). Conclusion The dyslipidemia in type 2 diabetic patients is one of the important risk factors of diabetic nephropathy.