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采用体外培养人淋巴细胞微核检测法,探讨复方云芝胶囊抗突变作用。结果表明,复方云芝胶囊(10mg/L~50mg/L)可显著抑制丝裂霉素C(MMC)诱发的微核形成,并可拮抗老年人自发微核,增加细胞增殖活性。
The in vitro culture of human lymphocyte micronucleus assay was used to investigate the antimutagenic effect of compound Yunzhi Capsule. The results showed that compound Yunzhi capsule (10mg/L ~ 50mg/L) can significantly inhibit the formation of micronucleus induced by mitomycin C (MMC), and can antagonize the spontaneous micronucleus of elderly people and increase the cell proliferation activity.