患男,76岁。因咽痛1次口服增效联磺片(每片含磺胺嘧啶0.2g、磺胺甲基异哑唑0.2g、甲氧苄胺嘧啶0.08g)6片.服后2h 全身皮肤瘙痒,4h 后有恶心及眼胀痛,急行洗胃,输液,未见好转,头痛,呕吐加重,视物模糊,第2d 症状持续加重,双眼失明转我院治疗.查体:全身检查正常.血、尿常规,胸透、心电图检查正常. Male, 76 years old. Sore throat acne 1 times due to synergistic joint tablets (each containing sulfadiazine 0.2g, sulfamethoxazole 0.2g, trimethoprim 0.08g) 6. 2h after taking systemic skin itching, after 4h Nausea and eye pain, urgency gastric lavage, infusion, no improvement, headache, vomiting, blurred vision, the first 2d symptoms continued to aggravate, blindness to our hospital treatment. Physical examination: systemic examination of normal blood, urine, Chest throat, normal ECG.