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目的探讨血清-腹水白蛋白梯度(Serum-ascites albumin gradient,SAAG)与门脉高压性食管静脉曲张破裂出血的关系,评价SAAG对预测门脉高压性食管静脉曲张破裂出血的价值。方法测定47例肝硬化腹水患者SAAG值并行胃镜检查以了解有无食管静脉曲张,以11g/L为界将47例患者分为高SAAG组及低SAAG组,分析SAAG与食管静脉曲张之间的关系。47例患者中并发食管静脉曲张破裂出血者15例,非出血者32例,测定两组患者的SAAG值并进行比较。结果 SAAG与食管静脉曲张、出血存在正相关关系(r=0.523,P<0.01;r=0.466,P<0.01);15例出血组患者其SAAG值为(22.67±4.47)g/L,32例非出血组患者其SAAG值为(17.25±5.21)g/L,两组比较差异有显著性(P<0.05)。结论 SAAG与门脉压力密切相关且对预测门脉高压性食管静脉出血有重要临床价值。
Objective To investigate the relationship between Serum-ascites albumin gradient (SAAG) and portal hypertensive esophageal variceal bleeding and evaluate the value of SAAG in predicting portal hypertension esophageal variceal bleeding. Methods Forty-seven patients with cirrhosis and ascites were examined by gastroscopy to understand the presence or absence of esophageal varices. 47 patients were divided into high SAAG group and low SAAG group with 11g / L as the boundary. The relationship between SAAG and esophageal varices relationship. Fifty-seven patients with esophageal variceal bleeding and 32 non-hemorrhage patients were included in the study. The SAAG values of the two groups were measured and compared. Results There was a positive correlation between SAAG and esophageal varices and hemorrhage (r = 0.523, P <0.01; r = 0.466, P <0.01). The SAAG value of 15 bleeding patients was 22.67 ± 4.47 g / The SAAG value of non-bleeding group was (17.25 ± 5.21) g / L, there was significant difference between the two groups (P <0.05). Conclusions SAAG is closely related to portal pressure and has important clinical value in predicting portal hypertension.