论文部分内容阅读
目的总结孤立性左室心肌致密化不全(ILVNC)患者的临床资料,并对其左室收缩功能的相关影响因素进行分析。方法连续入选自2006年1月至2010年9月经超声心动图确诊为ILVNC的患者共41例,总结其临床资料,并对可能影响该组患者左室射血分数(LVEF)的因素进行分析。结果 41例患者(男性35例)LVEF均值为31.41±11.21%;最常受累的心肌节段是心尖部(100%受累),其次是心尖段外侧壁(92.7%受累)、心尖段下壁(82.9%受累)和心尖段前壁(70.7%受累)。相关性分析表明,LogNT-proBNP、左室舒张末内径(LVEDD)和室壁运动评分指数(WMSI)与LVEF均呈负相关,r分别为-0.441(P=0.007)、-0.357(P=0.022)以及-0.714(P=0.000),具有显著的统计学意义;受累节段数目和NC/C比值则与LVEF无显著相关性;WMSI与受累节段数目呈正相关(r=0.362,P=0.020),与NC/C比值无显著相关性(P=0.254)。结论 ILVNC患者LVEF左室整体收缩功能与NT-proBNP及LVEDD呈负相关,而与受累心肌节段数目、NC/C比值无明显关联。
Objective To summarize the clinical data of patients with isolated left ventricular myocardium degeneration (ILVNC) and to analyze the influencing factors of left ventricular systolic function. Methods A total of 41 patients with ILVNC diagnosed by echocardiography from January 2006 to September 2010 were enrolled in this study. The clinical data were summarized and the factors influencing left ventricular ejection fraction (LVEF) in this group were analyzed. Results The mean LVEF of 41 patients (35 males) was 31.41 ± 11.21%. The most common myocardial segments were apical (100%), followed by the apical wall (92.7%), the inferior wall of the apical segment 82.9% involvement) and apical anterior segment (70.7% involvement). Correlation analysis showed that LogNT-proBNP, LVEDD and WMSI were negatively correlated with LVEF, r were -0.441 (P = 0.007), -0.357 (P = 0.022) And -0.714 (P = 0.000), with significant statistical significance. The number of involved segments and NC / C ratio had no significant correlation with LVEF. There was a positive correlation between WMSI and the number of involved segments (r = 0.362, P = 0.020) , No significant correlation with NC / C ratio (P = 0.254). Conclusion The left ventricular total systolic function of LVEF in patients with ILVNC is negatively correlated with NT-proBNP and LVEDD, but not with the number of involved myocardial segments and NC / C ratio.