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目的:探讨抗菌药物在临床的合理应用。方法:随机抽取1998年6月～12月出院病案143份(例),进行分析。结果:其中应用抗菌药物132例(92.3％)。132例中,用于治疗69例(52.3％),用于预防63例(47.7％)。细菌培养标本16份,培养阳性率31.5％。应用抗菌药物10大类43种1573用药日。不合理应用比例分别为39.4％(按例数算)及42.5％(按用药天数算)。不合理应用的主要原因是:非适应证用药和预防用药时间过长。结论:调查结果提示:①应及早制订本单位抗菌药物临床应用规范并认真贯彻执行。②强化临床医师合理应用抗菌药物的意识。③充分利用实验室条件进行细菌培养和药敏试验,以提高诊治水平。
Objective: To investigate the rational application of antibacterials in clinical practice. Methods: 143 cases (cases) discharged from June 1998 to December 1998 were randomly selected and analyzed. Results: Antibiotics were applied in 132 cases (92.3%). In 132 cases, 69 cases (52.3%) were treated for the prevention of 63 cases (47.7%). 16 bacterial culture specimens, culture positive rate of 31.5%. Application of antimicrobial drugs 10 categories 43 kinds of 1573 days of medication. The unreasonable application rates were 39.4% (calculated by the number of cases) and 42.5% (calculated on the days of the drug). The main reason for the unreasonable application is that the time for using non-indications and prophylaxis is too long. Conclusions: The findings suggest that: ① clinical application of antimicrobial agents should be formulated as soon as possible and implemented conscientiously. ② strengthen the rational use of antibiotics clinicians awareness. ③ full use of laboratory conditions for bacterial culture and susceptibility testing to improve the diagnosis and treatment level.