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目的探讨米非司酮配伍米索前列醇用于终止8～12周妊娠在人工流产中的应用。方法选择2008年3月至2009年3月来本院门诊要求终止妊娠,年龄在20～35岁之间,孕8～12周,无药物流产禁忌证者,于流产前2d口服米非司酮片,第3天来院行阴道后穹窿放置米索前列醇0.4mg,观察2～4h后行人工流产与未服用药物0.2%利多卡因局麻下直接行人工流产进行对照。结果应用米非司酮及米索前列醇后引产成功率高、出血量少、患者痛苦小、术后并发症少。结论米非司酮配伍米索前列醇用于终止8～12周妊娠,在人工流产中软化和扩张宫颈作用确切,患者痛苦小、操作简单、并发症少值得推广。
Objective To investigate the application of mifepristone combined with misoprostol for termination of pregnancy from 8 to 12 weeks in induced abortion. Methods From March 2008 to March 2009, our hospital required termination of pregnancy, aged 20 to 35 years old, pregnant 8 to 12 weeks without contraindications to drug abortion, oral mifepristone 2d before the abortion On the third day, 0.4% misoprostol was placed in the vaginal fornix, and induced abortion was observed after 2 ~ 4h with direct abortion under local anesthesia with no lidocaine 0.2%. Results Mifepristone and misoprostol after induction of high success rate, less bleeding, patients with less pain, less postoperative complications. Conclusions Mifepristone and misoprostol are used to terminate the pregnancy of 8 to 12 weeks. It is effective in softening and expanding cervix in induced abortion. It has less pain, simple operation and less complications.