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5. An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes

An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes

来源 :中国化学快报 | 被引量 : 0次 | 上传用户：smileman

【摘 要】

：

A simple and efficient procedure for synthesis of 1-hydroxymcthylene-1,1-bisphosphoates from aldehydes is deseribed. This method was applied to the synthesis of

【作 者】

：

Yu Li XIE Qin ZHU Xing Rong QI 

【机 构】

：

State Key Laboratory of Drug Research

【出 处】

：

中国化学快报

【发表日期】

：

2004年期

【关键词】

：

Bisphosphonate aldehydes catechol anti-osteoporosis 

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论文部分内容阅读

A simple and efficient procedure for synthesis of 1-hydroxymcthylene-1,1-bisphosphoates from aldehydes is deseribed. This method was applied to the synthesis of nowel catcchol substituted bisphosphonatcs as the anti-ostcoporosis agents.

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