目的探讨他汀类药物在调脂治疗过程中应该注意的不良作用。方法结合服用他汀类调脂药物后的不良临床表现进行分析。结果他汀类药物治疗过程中应密切注意患者的肌肉症状及腹胀、恶心、食欲缺乏、肝区不适等症状,并在用药后注意复查肝功能和肌酶谱,及早发现。结论在应用他汀类药物时应严格掌握适应证,权衡药物疗效和药物不良反应之间的关系,并采用较小剂量给药,以尽可能减少发生药物毒性反应的可能性。 Objective To investigate the adverse effects of statins in lipid-lowering therapy. Methods combined with statin lipid-lowering drugs after the poor clinical performance analysis. Results Statin therapy should pay close attention to patients with muscular symptoms and abdominal distension, nausea, loss of appetite, liver discomfort and other symptoms, and check the liver function and muscle enzymes after drug use, early detection. Conclusions The indications should be strictly applied when statins are used. The relationship between drug efficacy and adverse drug reactions should be weighed and the dose should be administered in a smaller dose in order to minimize the possibility of drug toxicity.