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目的:了解医用直线加速器的6MV-X射线在进行头颈部、胸部、下腹部肿瘤治疗时非靶器官睾丸的受照剂量,为优化临床治疗计划提供实验依据。材料与方法:将热释光剂量探测器(TLD)预置于非均匀组织等效拟人体模型睾丸内,然后以6MV-X射线分别仿鼻咽癌、食道癌、前列腺癌进行照射,根据TLD读数及标准方程推算出睾丸的剂量。结果:同一部位进行照射时,两侧睾丸剂量无明显差异,不同部位照射时,其睾丸的剂量有显著差异,头颈部、胸部、下腹部的靶区每Gy剂量照射对睾丸的剂量贡献分别为0.155mGy、0.340mGy、32.075mGy。结论:常规的下腹部肿瘤放射治疗对睾丸组织受照剂量较大,可用屏蔽的方法减少睾丸的受照剂量。
OBJECTIVE: To understand the dose of non-target organ testis of 6MV-X-ray in the treatment of head and neck, thorax and abdomen of the medical linear accelerator, and provide experimental basis for optimizing the clinical treatment plan. MATERIALS AND METHODS: TLDs were placed in testes of non-uniform tissue-equivalent artificial human model and then irradiated with 6MV-X radiation for nasopharyngeal carcinoma, esophageal carcinoma and prostate cancer respectively. According to TLD Readings and standard equations to calculate the testis dose. Results: There was no significant difference in the testis dose between the two sides when the same site was irradiated. The dose of testis was significantly different in different sites. The dose contribution of testis to the target area of head, neck, chest and lower abdomen were respectively 0.155 mGy, 0.340 mGy, 32.075 mGy. CONCLUSIONS: Conventional lower abdominal tumor radiotherapy has a greater dose of testis tissue irradiation and can be screened to reduce testis dose.