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目的探讨TORCH抗体检测的临床意义。方法用化学发光微粒子免疫检测法(CMIA)检测血清中的特异性抗弓形虫IgM/IgG抗体(TOX-IgM/IgG)、抗风疹病毒IgM/IgG抗体(RV-IgM/IgG)、抗巨细胞病毒IgM/IgG抗体(CMV-IgM/IgG),检测抗单纯疱疹病毒Ⅰ型和Ⅱ型IgM/IgG抗体(HSVⅠ/Ⅱ-IgM/IgG),分析感染率。结果与育龄妇女相比,新生儿的TOX、RV、CMV的IgM抗体阳性率均降低,差异有统计学意义(P<0.05),其余2项差异无统计学意义。新生儿的RV-IgG阳性率低于育龄妇女,差异有统计学意义(P<0.01),其余4项差异无统计学意义(P>0.05)。结论 TORCH的筛查对做好优生优育工作、提高出生人口素质具有重要意义。
Objective To investigate the clinical significance of detecting TORCH antibody. Methods Anti-Toxoplasma gondii antigens (TOX-IgM / IgG), RV-IgM / IgG, anti-Giant cells Virus IgM / IgG antibody (CMV-IgM / IgG) was used to detect the herpes simplex virus type I and IgM / IgG antibodies (HSVⅠ / Ⅱ-IgM / IgG). Results Compared with women of childbearing age, the positive rates of IgM antibodies in TOX, RV and CMV of newborns were all lower than those of women of childbearing age (P <0.05). There was no significant difference between the other two groups. The positive rate of RV-IgG in newborns was lower than that of women of childbearing age, the difference was statistically significant (P <0.01). There was no significant difference in the other 4 items (P> 0.05). Conclusion The screening of TORCH is of great importance to good prenatal and postnatal care and improving the quality of birth population.