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钙拮抗剂治疗慢性稳定性劳力性心绞痛的作用已经确定,但对最为广泛应用的异搏停与硝苯吡啶的有效性及安全性,尚未见有比较研究.为此,作者在慢性稳定性心绞痛病人中,对这二种钙拮抗剂作了随机双盲安慰剂对照的交叉研究.方法:(1)安慰剂与硝苯吡啶的双盲比较:24例慢性稳定性心绞痛病人,停用抗心绞痛药物至少4周.安慰剂与硝苯吡啶(10毫克,每日3次)的双
The role of calcium antagonists in the treatment of chronic stable angina pectoris has been determined, but there is no comparative study on the effectiveness and safety of the most widely used verapamil and nifedipine.Therefore, in the study of chronic stable angina pectoris Patients were randomized, double-blind placebo-controlled crossover study of these two calcium antagonists.Methods: (1) A double-blind comparison of placebo and nifedipine: 24 patients with chronic stable angina pectoris had anti-angina pectoris Medication for at least 4 weeks. Placebo double with nifedipine (10 mg, 3 times daily)