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目的探讨分析百令胶囊治疗早期糖尿病肾病患者的疗效。方法 80例早期糖尿病肾病患者,根据患者服药的不同分为治疗组和对照组,每组40例。对照组给予西药治疗,治疗组在对照组西药治疗基础上给予百令胶囊治疗。治疗6个月后评价疗效。结果治疗组总有效率为90.00%,高于对照组的65.00%,差异具有统计学意义(P<0.05)。治疗前及治疗后两组空腹血糖和餐后2 h血糖组间比较差异均无统计学意义(P>0.05);两组治疗后空腹血糖和餐后2 h血糖均较治疗前降低,差异均具有统计学意义(P<0.05)。两组治疗前血肌酐、血尿素氮以及24小时尿蛋白定量、血浆白蛋白比较差异均无统计学意义(P>0.05);治疗后两组血肌酐、血尿素氮以及24小时尿蛋白定量均较治疗前降低,血浆白蛋白较治疗前升高,且治疗组均优于对照组,差异均具有统计学意义(P<0.05)。结论西药常规治疗基础上给予百令胶囊对于早期糖尿病肾病患者肾功能具有很好的改善作用。
Objective To investigate the efficacy of Bailing capsule in the treatment of patients with early diabetic nephropathy. Methods Eighty patients with early diabetic nephropathy were divided into treatment group and control group according to the patients taking medicine, 40 cases in each group. The control group was treated with western medicine. The treatment group was treated with Bailing capsule on the basis of western medicine in the control group. After 6 months of treatment evaluation of efficacy. Results The total effective rate in the treatment group was 90.00%, which was higher than 65.00% in the control group, the difference was statistically significant (P <0.05). Before and after treatment, there was no significant difference in fasting blood glucose and postprandial 2-h blood glucose between the two groups (P> 0.05); fasting blood glucose and postprandial 2-hour blood glucose were decreased in both groups after treatment Statistically significant (P <0.05). Serum creatinine, blood urea nitrogen and 24-hour urinary protein in two groups before treatment did not show any significant difference (P> 0.05); after treatment, serum creatinine, blood urea nitrogen and 24-hour urine protein Compared with before treatment, plasma albumin increased, and the treatment group were better than the control group, the difference was statistically significant (P <0.05). Conclusions Bailing Capsule, which is based on routine treatment of western medicine, has a good effect on improving renal function in patients with early diabetic nephropathy.