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作者采用综合化疗后骨髓移植的方法治疗晚期急性白血病100例,其中急粒54例,急淋46例。患者接受1,000拉德全身照射后,取HLA相合的同胞骨髓进行移植。结果100例中死亡者83例,其主要原因是①移植物抗宿主病;②间质性肺炎;③白血病复发;④处理危急晚期的临床问题。存活者17例,4例复发,但2～4年半未死亡,其中急性淋巴细胞性者5例,粒细胞性者6例,都已完全缓解,并恢复正常活动。从治疗的病例看来,在处理急性白血病患者时,骨髓移植应在早期进行。
The author adopted the method of integrated chemotherapy and bone marrow transplantation in the treatment of advanced acute leukemia in 100 cases, of which acute grain in 54 cases, 46 cases of acute lymphoblastic. Patients receiving 1,000 rad after whole body irradiation, HLA-matched siblings marrow transplantation. Results 83 cases of death in 100 cases, the main reason is ① graft-versus-host disease; ② interstitial pneumonia; ③ leukemia relapse; ④ deal with the clinical problems of critical late. Survival in 17 cases, 4 cases of recurrence, but 2 to 4 years and a half did not die, of which 5 cases of acute lymphocytic and granulocytic in 6 cases, have been completely relieved and returned to normal activity. It seems from the treatment of patients in the treatment of acute leukemia patients, bone marrow transplantation should be carried out in the early.