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[目的]了解肺螨病的流行状况、分布特征与治疗效果,为大面积防治本病提供科学依据。[方法]2000年6月至2006年6月,采用询问病史、螨渗液皮试、痰检等方法,在济宁市部分粮库、粮食加工厂、农村磨坊、中药房(库)、中药厂、卷烟厂和图书馆(室)的工作人员中进行调查,对确诊的肺螨病病人进行治疗效果观察。[结果]调查2 113人,确诊肺螨病者160例,患病率为7.57%。肺螨病患病率,农村磨坊、面粉厂、粮库、中药店、中药厂、图书馆(室)、烟厂工作人员分别为14.53%、11.11%、8.39%、7.14%、6.12%、5.06%、4.15%,其他对照人群96人均为阴性(P<0.01);46岁以上、36~45岁、26~35岁和16~25岁分别为14.19%、9.81%、7.94%、3.41%(P<0.01);工龄0~9、10~19年、20~29年、30年以上者分别为5.81%、8.49%、16.18%、23.53%(P<0.01)。痰检685人,痰螨阳性的160例,检出的螨有12种,分隶属5科10属。160例病人服用甲硝哒唑治疗3个疗程,141例自觉症状消失或改善;痰检133例,126例痰螨阴性。[结论]肺螨病的发病与职业有密切关系,采用甲硝哒唑治疗效果显著。
[Objective] To understand the prevalence, distribution characteristics and treatment effect of pulmonary mite disease and provide scientific basis for prevention and treatment of this disease in large area. [Methods] From June 2000 to June 2006, the medical history, mite exudate skin test and phlegm test were used in some grain depots, grain processing plants, rural mills, pharmacies (libraries), traditional Chinese medicine factories , Cigarette factory and library (room) staff were investigated, the diagnosis of pulmonary mite patients for treatment effect. [Results] The survey of 2 113 people, diagnosed pulmonary mite disease in 160 cases, the prevalence was 7.57%. The prevalence of lung mite diseases was 14.53%, 11.11%, 8.39%, 7.14%, 6.12% and 5.06 respectively in rural mills, flour mills, grain depots, Chinese medicine shops, Chinese medicine factories, % And 4.15%, respectively. The other 96 control groups were negative (P <0.01). The average age of patients over 46 years old, 36-45 years old, 26-35 years old and 16-25 years old were 14.19%, 9.81%, 7.94% and 3.41% P <0.01). The length of service was 5.81%, 8.49%, 16.18% and 23.53% respectively (P <0.01) after working for 0-9, 10-19, 20-29, and 30 years. Sputum examination of 685 people, sputum mites positive 160 cases, detected 12 kinds of mites, sub-5 families and 10 genera. 160 cases of patients taking metronidazole treatment of three courses, 141 cases of symptoms disappeared or improved; sputum examination in 133 cases, 126 cases of sputum mites negative. [Conclusion] The incidence of pulmonary mite disease is closely related to occupation. The treatment with metronidazole is remarkable.