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目的观察阿苯达唑化疗对肝包虫患者肝功能及外周血白细胞影响。方法随机选择24例肝包虫患者给予A1b片口服治疗,20 mg/(kg.d),每个疗程4周,治疗6个月,检查肝功和外周白细胞。结果 24例包虫患者口服A1b3个月时54.17%肝功能异常,6个月时33.33%肝功能异常,与治疗前分别相比差异均有统计学意义(P<0.01和P<0.05),患者肝功能损害差异无统计学意义。结论 A1b用于肝包虫患者治疗对于肝功能有影响但是安全的。
Objective To observe the effects of albendazole chemotherapy on hepatic function and peripheral leukocytes in hepatic hydatid disease patients. Methods Twenty-four patients with hepatic hydatid were randomized to oral treatment with A1b tablets at 20 mg / (kg · d) for 4 weeks each for 6 months. Liver function and peripheral white blood cells were examined. Results In 24 cases of hydatid disease patients, 54.17% of liver function abnormalities at A1b3 months and 33.33% of liver dysfunction at 6 months were statistically different from those before treatment (P <0.01 and P <0.05) No significant difference in liver dysfunction. Conclusions A1b is safe but safe for liver function in patients with hepatic hydatid disease.