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目的观察米非司酮配伍米索前列醇治疗稽留流产的临床效果。方法选取稽留流产患者150例,采取数字随机法分成观察组和对照组各75例,观察组采用米非司酮配伍米索前列醇治疗,对照组采取戊酸雌二醇治疗,比较2组临床效果。结果观察组完全流产率高于对照组,不完全流产率低于对照组,排胎后2h阴道出血量少于对照组,差异均有统计学意义(P<0.05)。2组流产失败率、用药后至排胎时间、用药不良反应发生率比较,差异均无统计学意义(P>0.05)。结论米非司酮配伍米索前列醇治疗稽留流产临床效果显著,安全有效,具有较高的可行性。
Objective To observe the clinical effect of mifepristone and misoprostol in treating missed abortion. Methods 150 patients with missed abortion were selected and randomly divided into observation group and control group with 75 cases in each group. The observation group was treated with mifepristone and misoprostol. The control group was treated with estradiol valerate. effect. Results The abortion rate of the observation group was higher than that of the control group, the rate of incomplete abortion was lower than that of the control group, and the amount of vaginal bleeding 2h after the rowing was less than that of the control group. The difference was statistically significant (P <0.05). There was no significant difference in the failure rate of abortion, the time from administration to rowing, and the incidence of adverse drug reactions (P> 0.05). Conclusion Mifepristone with misoprostol in the treatment of missed abortion clinical effect is significant, safe and effective, with high feasibility.