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目的分析深圳市龙岗区手足口病流行病学特征和流行趋势,探讨更为有效的防控措施。方法对龙岗区2008-2011年手足口病报告病例、重症病例和病原学监测资料进行分析。结果龙岗区4年共报手足口病病例28 948例,年平均发病率183.13/10万;重症病例102例,占病例总数的0.35%;死亡18例,占重症病例的17.65%,占全部病例的0.062%。病例男性多于女性,0～3岁散居儿童是发病、重症和死亡病例的高发人群,4～7月为发病高峰月份。EV71是主要病原体。男性患儿发生重症的概率(389/10万)高于女性(290/10万),差异有统计学差异(2=14.48,P<0.001)。结论 2008-2011年手足口病流行强度逐年增强,应重点加强0～3岁低幼龄儿童的社区防控力度和提高重症病例的早期识别能力和救治力度。
Objective To analyze the epidemiological characteristics and trends of HFMD in Longgang District of Shenzhen City and to explore more effective prevention and control measures. Methods The reported cases of HFMD in 2008-2011 in Longgang District were analyzed. The data of severe cases and etiology were also analyzed. Results A total of 28 948 hand-foot-mouth disease cases were reported in Longgang district in 4 years, with an average annual incidence of 183.13 / 100,000; 102 cases of severe disease, accounting for 0.35% of the total cases; 18 cases of death, accounting for 17.65% of severe cases, accounting for all cases Of 0.062%. More cases of males than females, 0-3 year-old scattered children is a high incidence of cases of critically ill and deaths, 4 to 7 months for the peak incidence month. EV71 is the major pathogen. The incidence of severe illness in males was higher than that of females (389/10 million) (290/10 million). The difference was statistically significant ( 2 = 14.48, P <0.001). Conclusion The epidemic intensity of hand, foot and mouth disease in 2008-2011 is increasing year by year. The emphasis should be put on strengthening the community prevention and control of young children aged 0-3 years and improving the early identification ability and treatment of severe cases.