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以对-吡唑基苯甲醛(1a)[或对-1,2,4-三唑基苯甲醛(1b)]和苯乙酮经Aldol缩合反应得4-吡唑查尓酮(2a)[或4-三唑查尔酮(2b)];2a或2b与2-乙酰基吡啶(3)经Michael加成反应得1-苯基-5-(2-吡啶基)-3-[4-(1-吡唑基)苯基]-1,5-戊二酮(4a)或1-苯基-5-(2-吡啶基)-3-[4-(1-[1,2,4]-三唑基)苯基]-1,5-戊二酮(4b);4a或4b与AcONH4经关环反应合成了两种新型含吡唑和三唑基的联吡啶衍生物——6-苯基-4-[4-(1H-吡唑基)苯基]-2,2’-联吡啶(5a)或6-苯基-4-[4-(1H-1,2,4-三唑基)苯基]-2,2’-联吡啶(5b),其结构经1H NMR,IR,MS和元素分析表征。UV-Vis和FL研究结果表明:5a和5b的λmax分别位于290 nm和280nm;5a和5b的λem均位于360 nm。
Pyrazole benzaldehyde (1a) [or p-1,2,4-triazolylbenzaldehyde (1b)] and acetophenone were subjected to Aldol condensation to give 4-pyrazoloxazolone (2b)]; Michael addition reaction of 2a or 2b with 2-acetylpyridine (3) gave 1-phenyl-5- (2-pyridyl) -3- [4- (1-pyrazolyl) phenyl] -1,5-pentanedione (4a) or 1-phenyl-5- ] -triazolyl) phenyl] -1,5-pentanedione (4b). Two novel pyrazole and triazole-based bipyridine derivatives, 4a and 4b, were synthesized via ring closure reaction with AcONH4 (5a) or 6-phenyl-4- [4- (1H-1,2,4-oxadiazol- Triazolyl) phenyl] -2,2’-bipyridine (5b) whose structure was characterized by 1H NMR, IR, MS and elemental analysis. The UV-Vis and FL results show that the λmax of 5a and 5b are located at 290 nm and 280 nm, respectively. The λem of both 5a and 5b are located at 360 nm.