结肠癌不伴淋巴结转移的病例不常规应用辅助性化疗，一则化疗的效益仅在15％病人有收益，二则缺乏有效的病例选择标准。Folkman提出血管生成与癌肿的转移有关，作者试用血管计数和血管内皮生长因子（VEGF）作为判定淋巴结阴性结肠癌病例伴发后期远处转移的可能性。作者取Texas Cases of colon cancer without lymph node metastasis are not routinely treated with adjuvant chemotherapy. The benefit of one chemotherapy is that only 15% of patients have benefit, and the second one lacks effective case selection criteria. Folkman proposed that angiogenesis is related to the metastasis of cancer. The authors tried blood vessel counts and vascular endothelial growth factor (VEGF) as a possibility to determine late-stage metastasis in cases of lymph node-negative colon cancer. The author takes Texas