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洋地黄样免疫反应物质(DLIS)是一种分子量<1,000 Da的水溶性和内源性热稳定因子,能与洋地黄抗体发生交叉反应,并具有促尿钠排泄活性并对Na~+,K~+-ATP酶有抑制作用。作者检测了慢性肝病,尤其是失代偿期患者及正常者的血清DLIS、血清肌酐、尿DLIS、尿钠等含量,以研究它们之间的相互关系和影响因素,并测血压、脉搏以评价其对DLIS的影响。
The digitalis-like immunoreactive substance (DLIS) is a water-soluble and endogenous thermal stabilizer with a molecular weight <1,000 Da that cross-reacts with digitalis antibodies and has natriuretic and anti-natriuretic activity against Na +, K ~ + -ATP enzyme inhibition. The authors examined the serum levels of DLIS, serum creatinine, urinary DLIS, urinary sodium, etc. in patients with chronic liver disease, especially in decompensated patients and normal subjects, to study their correlation and influencing factors, and to measure blood pressure and pulse rate to evaluate Its impact on DLIS.