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目的分析和探讨重症消化性溃疡上消化道大出血的临床治疗方案。方法 110例重症消化性溃疡上消化道大出血患者,随机分为对照组和观察组,各55例。对照组采用奥美拉唑治疗,观察组患者给予泮托拉唑治疗,观察并详细记录两组患者临床疗效。结果连续治疗1周后,观察组治疗总效率为98.18%,对照组治疗总有效率为90.91%,观察组临床疗效明显优于对照组,差异有统计学意义(P<0.05)。结论在重症消化性溃疡上消化道大出血的临床治疗中,采用泮托拉唑能有效地提高治疗有效率,缩短止血时间,不良反应少,安全可靠,值得临床推广与应用。
Objective To analyze and discuss the clinical treatment of upper gastrointestinal bleeding in severe peptic ulcer. Methods A total of 110 patients with severe peptic ulcer bleeding in upper gastrointestinal tract were randomly divided into control group and observation group, with 55 cases in each group. The control group was treated with omeprazole. The patients in the observation group were treated with pantoprazole. The clinical efficacy was observed and recorded in detail. Results After one week of continuous treatment, the total effective rate of the observation group was 98.18%, while the total effective rate of the control group was 90.91%. The clinical efficacy of the observation group was significantly better than that of the control group (P <0.05). Conclusion In the clinical treatment of upper digestive tract hemorrhage in severe peptic ulcer, the use of pantoprazole can effectively improve the treatment efficiency, shorten the time to stop bleeding, fewer adverse reactions, safe and reliable, and worthy of clinical promotion and application.