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目的 探讨脑出血后二周内早期癫痫发作的发生率、临床特征及预后。方法 对 10 5 0例确诊为脑出血患者的临床资料进行分析。结果 脑出血后早期癫痫发生率为 6 .19%。早期癫痫发作与出血部位(皮层或脑叶 )的关系密切。降颅内压脱水治疗及抗癫痫药物对脑出血后早期癫痫发作大多有效 ,但伴发早期癫痫的脑出血病死率为 2 7.6 9% ,并明显高于无继发癫痫的脑出血病死率 18.98% (P <0 .0 1)。结论 脑出血后伴早期癫痫发作多见于皮层脑叶出血 ,且以全身性发作为主 ,脱水和抗癫痫药治疗有效 ,但临床预后较差。
Objective To investigate the incidence, clinical features and prognosis of early epileptic seizures within two weeks after intracerebral hemorrhage. Methods The clinical data of 105 cases diagnosed as cerebral hemorrhage were analyzed. Results The incidence of early epilepsy after ICH was 6.19%. Early seizures and bleeding site (cortex or lobule) are closely related. Decreased intracranial pressure dehydration and antiepileptic drugs are mostly effective for early epileptic seizures after intracerebral hemorrhage, but the mortality rate of intracerebral hemorrhage with early epilepsy is 2 7.69%, which is significantly higher than the mortality of cerebral hemorrhage without secondary epilepsy % (P <0 .0 1). Conclusions Cerebral hemorrhage followed by early seizure is more common in cortical lobar hemorrhage and is mainly systemic. Dehydration and antiepileptic drugs are effective, but the clinical prognosis is poor.