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目的探讨脾动脉栓塞术治疗肝硬化合并脾功能亢进的疗效和安全性。方法 48例肝硬化合并脾功能亢进患者均进行脾动脉栓塞术治疗,观察手术前后脾功能亢进改善情况。结果进行脾动脉栓塞术治疗后的有效率为95.8%(46/48),随访6个月,1例复发,复发率为2.1%(1/48)。手术后,患者白细胞(WBC)、红细胞(RBC)、血红蛋白(Hb)、红细胞压积(HCT)、血小板(PLT)水平均显著高于手术前,差异具有统计学意义(P<0.05)。结论脾动脉栓塞术可以作为肝硬化合并脾功能亢进理想的治疗方法 ,值得临床应用及推广。
Objective To investigate the efficacy and safety of splenic arterial embolization in the treatment of liver cirrhosis complicated with hypersplenism. Methods Forty-eight patients with cirrhosis and hypersplenism were treated with splenic arterial embolization. The improvement of hypersplenism before and after operation was observed. Results The effective rate was 95.8% (46/48) after splenic arterial embolization. The recurrence rate was 2.1% (1/48) in one case after 6 months of follow - up. After operation, the levels of white blood cells (WBC), red blood cells (RBC), hemoglobin (Hb), hematocrit (HCT) and platelet (PLT) in patients were significantly higher than those before operation (P <0.05). Conclusion Splenic artery embolization can be used as an ideal treatment for liver cirrhosis combined with hypersplenism, which is worthy of clinical application and promotion.