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作者报告了6例慢性心脏病人,由于短暂性循环衰竭所导致的暴发性肝衰竭。6例均经病理证实(其中3例经肝活检,3例经尸检),组织学所见均为块状的小叶中心性坏死而不伴有炎细胞浸润。本组暴发性肝衰竭的主要临床表现为扑翼样震颤、精神错乱或昏迷、黄疸和转氨酶的显著升高。文章总结了6例的特点为:1.6例中5例年龄在60岁以上;2.肝脏损害均由在慢性心脏病心衰基础上,又出现短暂性急性循环衰竭所致,其中消化道出血导致失血性休克3例,心源性休克1例,急性肺水肿1例,心跳突停1例;3.暴发性肝衰竭的
The authors report six patients with chronic heart disease due to transient circulatory failure caused by fulminant hepatic failure. Six cases were pathologically confirmed (of which three were liver biopsy, three were autopsy), histological findings are massive lobular necrosis without inflammatory cell infiltration. The main clinical manifestations of fulminant hepatic failure in this group were asymptomatic tremor, confusion or coma, jaundice and transaminase were significantly higher. The article summarizes the features of 6 cases: 5 of 1.6 cases were over 60 years of age; 2. Liver damage was caused by transient acute circulatory failure on the basis of heart failure of chronic heart disease, in which gastrointestinal bleeding resulted 3 cases of hemorrhagic shock, 1 case of cardiogenic shock, 1 case of acute pulmonary edema, 1 case of cardiac arrest; 3 cases of fulminant hepatic failure